ESMMS contains a collection of review chapters written by renowned researchers in statistics (11 of the original 27 chapters from HS27), with the aim of providing a suitably broad, yet concise, survey of traditional and emerging topics in biomedical statistics. ESMMS is targeted to applied statisticians, with an emphasis on applications-oriented methodology. Most chapters proceed in a gentle introductory manner, but do presume a general familiarity with calculus, probability theory, and statistical modeling (random variables, likelihood functions, maximum likelihood estimation, etc.) at the level of a graduate course in biostatistics… In summary, I do believe ESMMS achieves its basic goal of providing an approachable general reference for applied statisticians. Virtually the entire text is well written, and it covers most of the material one would expect to find in such a volume. However, my own preference is for more targeted material (with specific code examples). As I sit at my desk writing this review, I am able to point to a targeted textbook for each and every chapter of ESMMS lying on the single bookshelf above my computer. In addition, while ESMMS does provide a slightly more technical treatment (and is obviously more current) than an entry-level biostatistics text, such as Fisher and Van Belle (1993), it is not clear to me whether this brings a great deal of added benefit. With that said, my recommendation for the applied statistician in search of a one-stop overview of biostatistics would be to spend the extra money and get HS27. While it is almost triple the cost, I would hazard to guess that it would be more useful, given the extensive amount of material it covers.
